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Injecting 5% phenol in oil into the rectal submucosa effectively treated rectal prolapse in 91% of young children. This suggests the condition primarily affects the rectal mucosa in children.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Colorectal Surgery
Background:
- Rectal prolapse is a common condition in young children.
- The exact pathophysiology of pediatric rectal prolapse remains debated.
- Previous treatments have varied in efficacy and invasiveness.
Purpose of the Study:
- To evaluate the efficacy of submucosal phenol in oil injections for treating persistent rectal prolapse in children.
- To investigate the underlying mechanism of common rectal prolapse in pediatric patients.
Main Methods:
- A cohort of 100 young children with persistent rectal prolapse was treated.
- The treatment involved injecting 5% phenol in oil into the rectal submucosa.
- Outcomes were assessed based on the resolution of rectal prolapse.
Main Results:
- The injection successfully cured rectal prolapse in 91 out of 100 children (91% cure rate).
- The treatment was well-tolerated with no significant adverse events reported.
- The high success rate indicates a specific therapeutic target.
Conclusions:
- Submucosal injection of 5% phenol in oil is a highly effective treatment for persistent rectal prolapse in children.
- These findings support the hypothesis that pediatric rectal prolapse primarily involves the rectal mucosa.
- The muscular wall appears to be secondarily affected, suggesting a targeted treatment approach is beneficial.
Abstract:
The injection of 5% phenol in oil into the rectal submucosa cured persistent rectal prolapse in 91 of 100 young children. This result supports the view that the common form of rectal prolapse in otherwise-healthy children primarily involves the mucosa and the muscular wall is only secondarily involved.