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Published on: January 3, 2018
Electrochemically Enabled Sulfenylation of Imidazo[1,2-a]pyridines Using Sodium Sulfinates
Jiusi Yang1, Wenxuan Zhan1, Jiasheng Wang1
1Biomass Oligosaccharides Engineering Technology Research Center of Anhui Province, Engineering Research Center of Biomass Conversion and Pollution Prevention of Anhui Educational Institutions, School of Chemistry and Material Engineering, Fuyang Normal University, Fuyang, Anhui 236037, P. R. China.
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An electrochemical method for the C-H sulfenylation of imidazo[1,2-a]pyridines has been developed, employing sodium sulfinates as odorless sulfenylation reagents. This approach provides efficient access to a range of C-3-sulfenated imidazo[1,2-a]pyridines in moderate to good yields. The reaction proceeds smoothly under electrochemical conditions without the need for external chemical oxidants and exhibits a broad substrate scope, which offers a promising new strategy for C-S bond formation using odorless sulfenylation reagents.
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