Related Experiment Video
Updated: Jun 19, 2026
Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position
Published on: August 17, 2017
Age-related macular degeneration and secondary fracture risk in patients with hip fractures
1The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
Abstract:
Research on the relationship between age-related macular degeneration (AMD) and secondary fracture risk following hip fractures is scant. We aimed to examine whether AMD increases the risk of secondary fractures following hip fracture surgery. This retrospective cohort study was conducted using data from the Korean National Health Insurance Service Senior Cohort (2002-2019). Secondary fractures were defined as hip, wrist, humerus, spine, ankle, or pelvic fractures occurring within 6 months after hip fracture surgery. Patients diagnosed with AMD within 6 months postoperatively were identified. Covariates included age, sex, income, insurance type, Charlson Comorbidity Index, residential area, disability status, and hospital size and type. Associations between AMD and secondary fractures were analyzed using Cox proportional hazards models. Among 18 611 patients with hip fractures, 93 were diagnosed with AMD and 26 experienced secondary fractures. Patients with AMD had a significantly higher risk of secondary fractures than those without AMD (adjusted hazard ratio, 1.70; 95% confidence interval, 1.16-2.51). Overall, AMD was associated with an increased risk across all fracture types. Effective management of AMD may help reduce the risk of secondary fractures.
Related Concept Videos
01:29Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:27Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...