Related Experiment Video
Updated: Jun 19, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
Published on: July 29, 2013
A standardized approach to technical image quality assessment in digital breast tomosynthesis using a commercial
A Barcella1, C Tenconi2, A Sarno1
1Department of Physics, University of Milan, Milano, Italy; INFN Section of Milan, Milano, Italy.
Purpose:
This study aimed to establish standardized methodologies for analysing Digital Breast Tomosynthesis (DBT) images acquired during technical image quality control tests using the CIRS Model 021 DBT Phantom.
Methods:
Procedures were developed to compute the z-Point Spread Function (z-PSF) and the z-Response Function (z-RF) using a tungsten wire tilted relative to the detector plane, the Artifact Spread Function (ASF) from a grid of ceramic beads, the Signal-Difference-to-Noise Ratio (SDNR) from a set of spheroidal masses. Phantom slabs were assembled in different configurations, with each exposure repeated seven times on three DBT system models to assess reproducibility.
Results:
All methods demonstrated reproducibility within 5%, with ASF measurements showing variability of 1%. The z-resolution of a 40-degree acquisition angle DBT system was 1.22 ± 0.05 mm for stacks of reconstructed planes that were 1 mm thick. The correspondence between the visually identified plane of focus in the reconstructed images and the peak of the ASF profile was within 0.5%. In plane geometric distortion values were verified to be within 1%.
Conclusions:
The ASF metric offers an efficient means for evaluating z-geometric distortion, while the z-PSF and z-RF metrics provide a more appropriate quantification of z-resolution. The investigated z-RF method enhances reproducibility and removes the need to calculate the wire's tilt angle, offering a simplified and reliable approach for routine quality control.
More Related Videos
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography

