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Oral white sponge nevus in patients with ectrodactyly-ectodermal dysplasia-cleft syndrome: two patients treated with

Paula Gerlero1, Silvia Vanessa Lourenço2, Marcello Menta Simonsen Nico1

  • 1Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil.

Anais Brasileiros De Dermatologia
|June 17, 2026
PubMed
Abstract

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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