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Allergic Rhinitis in the Elderly. In Collaboration With the ARIA Guidelines
Jean Bousquet1, Maria Teresa Ventura2, Luis Taborda-Barata3
1Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany; ARIA (Allergic Rhinitis and its Impact on Asthma), Montpellier, France.
Allergic rhinitis (AR) in older adults is complex, often co-occurring with non-allergic rhinitis (NAR) and presenting unique diagnostic challenges. Safe and effective management focuses on intranasal corticosteroids and second-generation antihistamines, avoiding older medications.
Area of Science:
- Otolaryngology
- Geriatrics
- Allergology
Background:
- Rhinitis in the elderly presents unique clinical challenges due to multimorbidity, frailty, and polypharmacy.
- Allergic rhinitis (AR) in older adults is frequently intertwined with non-allergic rhinitis (NAR).
- Symptoms like nasal dryness and congestion without clear triggers can lead to underrecognition.
Purpose of the Study:
- To highlight the complexities of diagnosing and managing rhinitis in the elderly population.
- To emphasize the need for person-centered treatment strategies.
- To review current therapeutic options and safety considerations for elderly patients with AR.
Main Methods:
- Review of existing literature on rhinitis in the elderly.
- Analysis of age-related changes affecting nasal function and symptom presentation.
- Evaluation of current treatment guidelines and pharmacological safety profiles.
Main Results:
- AR in the elderly often presents atypically, complicating diagnosis.
- Age-related nasal changes can influence symptom perception and presentation.
- First-generation antihistamines should be avoided due to safety concerns.
Conclusions:
- Management of AR in the elderly requires careful consideration of comorbidities and polypharmacy.
- First-line treatments include intranasal corticosteroids (INCS) and second-generation oral antihistamines.
- Digital health and artificial intelligence show promise for future AR management in this demographic.
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