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Updated: Jun 19, 2026

Mouse Model of Oleic Acid-Induced Acute Respiratory Distress Syndrome
Published on: June 2, 2022
Repeated Self-induced Vomiting-associated Exogenous Lipoid Pneumonia Following Occult Olive Oil Aspiration
Hazuki Takato1, Tamami Sakai1, Takayuki Higashi1
1Department of Respiratory Medicine, National Hospital Organization Kanazawa Medical Center, Japan.
Abstract:
We report a case of exogenous lipoid pneumonia, which was possibly caused by the chronic aspiration of olive oil during recurrent self-induced vomiting episodes. A 28-year-old woman with a history of depression, self-induced vomiting, and type 1 diabetes was referred because of abnormal chest radiography findings during screening. Chest CT revealed ground-glass opacities, predominantly in the right middle and lower lobes. A bronchoalveolar lavage fluid examination revealed a bi-layer separation of lipid-laden macrophages from the cell suspension. Diagnostic video-assisted thoracoscopy confirmed the diagnosis of exogenous lipoid pneumonia. Following the cessation of olive oil intake, her radiologic abnormalities improved without steroid therapy.
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