Related Experiment Video
Updated: Jun 19, 2026

04:41
Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
Published on: July 28, 2023
Modified Surgical Technique Combined with Radiation Therapy for Keloid Management
Xueqing Wang1,2, Kai Xie1,2, Yilei Wu1,2
1Department of Dermatologic Surgery, Dermatology Hospital of Shandong First Medical University, Jinan, 250000, Shandong, China.
Aesthetic Plastic Surgery
|June 17, 2026
Summary
A modified surgical technique combined with radiation therapy shows promise for treating keloids, significantly improving scar appearance and reducing recurrence rates in a patient study.
Area of Science:
- Dermatology
- Surgical Oncology
- Radiation Oncology
Background:
- Keloids are challenging skin lesions with high recurrence rates after treatment.
- Current treatments, including surgical excision with radiotherapy, have limitations.
- High recurrence rates necessitate improved therapeutic strategies for keloid management.
Purpose of the Study:
- To evaluate the efficacy of a modified surgical excision technique combined with radiotherapy for keloid treatment.
- To assess the impact of the modified technique on scar appearance using the Vancouver Scar Scale (VSS).
Main Methods:
- A modified surgical technique reducing wound tension was applied to 89 patients.
- The procedure involved excising keloids and applying radiotherapy.
- Scar appearance was evaluated using the Vancouver Scar Scale (VSS) post-treatment.
Main Results:
- Follow-up ranged from 12 to 28 months (average 16.4 months).
- Local recurrence was observed in 14.6% of patients.
- A significant decrease in mean VSS scores indicated improved scar cosmetic appearance (P < 0.001).
Conclusions:
- The modified surgical technique with radiation therapy appears effective for keloid treatment.
- This approach may offer a better cosmetic outcome and reduced recurrence.
- Further research could validate this method for keloid management.