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Artificial intelligence and medical futility.
Sinead Prince1, Dominic J C Wilkinson2,3, G Owen Schaefer4
1Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Drive, #02-03 MD11, Singapore, 117597, Singapore. sprince@nus.edu.sg.
BMC Medical Informatics and Decision Making
|June 18, 2026
Summary
Artificial intelligence (AI) may help resolve medical futility disputes, but risks like self-fulfilling prophecies exist. Ethical integration and regulation are key for AI to assist in end-of-life care decisions.
Area of Science:
- Medical Ethics
- Artificial Intelligence in Healthcare
- End-of-Life Care
Background:
- Medical futility determination is complex, involving conceptual, empirical, and ethical disputes.
- These disputes create significant challenges for patients, families, healthcare providers, and legal systems.
- There is a practical need to resolve futility questions in individual cases.
Purpose of the Study:
- To explore the ethical and practical implications of using artificial intelligence (AI) in medical futility decisions.
- To assess whether AI tools can ethically and effectively assist in resolving futility disputes.
- To analyze the potential benefits and risks of AI in end-of-life care decision-making.
Main Methods:
- A critical narrative review of existing scholarship on medical futility ethics.
- Survey of current and potential medical AI applications relevant to futility.
- Philosophical analysis of AI's ethical use, applying principles like autonomy, beneficence, and justice.
Main Results:
- AI use in futility determination carries risks, such as exacerbating self-fulfilling prophecies.
- Under specific conditions, medical AI can ethically aid in preventing or resolving futility disputes.
- Careful consideration of AI's role is necessary to mitigate potential negative impacts.
Conclusions:
- AI holds potential to ethically contribute to preventing and resolving medical futility disputes.
- The ethical application of AI in this context depends heavily on its integration and regulation.
- Responsible implementation is crucial for AI to support ethical end-of-life care decision-making.
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