Related Experiment Video
Updated: Jun 19, 2026

Multi-Modal Signals for Analyzing Pain Responses to Thermal and Electrical Stimuli
Published on: April 5, 2019
[Pain reprocessing therapy : from an alarm signal to a sense of safety]
Luzia Grabherr1,2, Chantal Berna1,2
1Centre de médecine intégrative et complémentaire, Service d'anesthésiologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
Chronic pain, particularly nociplastic pain, is a common challenge in outpatient practice. Pain reprocessing therapy (PRT) is a therapeutic approach aimed at modifying the brain's interpretation of pain and breaking the fear-pain cycle. Drawing from theories and research on neuroplasticity and central sensitization, PRT proposes reframing symptoms as potentially harmless signals. Recent randomized controlled trials, including one with long-term follow-up, show a significant and sustained reduction in pain. This article summarizes the current research, conceptual foundations, available training programs, therapeutic techniques, and integration of PRT into practice, with an example from the clinical practice at the CHUV.
Related Concept Videos
Pain
Nociception
Desensitization and Tachyphylaxis
Several...
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Role of Amygdala in Memory
One of the...

