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Primary Endometrium Primitive Neuroectodermal Tumor with Diagnostic and Treatment Challenges: A Case Report
Haoyun Zhao1, Lu Yang1, Ya Shi1
1Department of Obstetrics and Gynecology, Jinling Hospital, Affiliated Hospital of Medical, Nanjing University, Nanjing, Jiangsu, 210000, People's Republic of China.
International Journal of Women'S Health
|June 18, 2026
Summary
Primary endometrial primitive neuroectodermal tumor (PNET) is rare and aggressive. Early diagnosis via immunohistochemistry is crucial for treatment and improving outcomes in young women with uterine bleeding.
Area of Science:
- Gynecologic Oncology
- Pathology
- Oncology
Background:
- Primitive neuroectodermal tumor (PNET) is a rare, aggressive malignancy.
- Primary endometrial PNET is uncommon and often misdiagnosed due to nonspecific features.
- Delayed diagnosis of endometrial PNET leads to poor prognosis.

