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Updated: Jun 19, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Weekend headache in migraine - fact or fiction? An observational study from DMKG-app data
Ruth Ruscheweyh1, Thomas Dresler2,3,4, Gudrun Gossrau5
1Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.
Cephalalgia : an International Journal of Headache
|June 18, 2026
Summary
A subgroup of migraine patients experience headaches on weekends. This weekend headache pattern is linked to working status and lower headache frequency, suggesting stress release may be a trigger.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Migraine is a common neurological disorder.
- Weekend headache in migraine patients has been proposed but findings are inconsistent.
- Electronic diaries allow for larger population studies.
Purpose of the Study:
- To investigate the existence and prevalence of weekend headache in migraine patients.
- To identify predictive factors for weekend headache.
Main Methods:
- Analysis of two large, independent samples from the DMKG-App electronic headache diary.
- Utilized cluster analysis and logistic regression to identify headache patterns and associated factors.
Main Results:
- A distinct cluster of patients with weekend-predominant migraine was identified in both samples (14-15% of patients).
- Weekend headache was more prevalent in working individuals and those with lower headache frequency.
- Older age showed a minor association in one sample; headache patterns varied longitudinally.
Conclusions:
- Confirms a subgroup of migraine patients prone to weekend headaches.
- Working status association supports stress-release as a potential trigger.
- Other factors like sleep, caffeine, and alcohol may also contribute.
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