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Endocrine Therapy and Fat Necrosis After IORT: Drug Effect or Follow-up Artifact?

Xiaoshan Huang1, Wenwei Song1

  • 1Department of Clinical Laboratory, The Second Affiliated Hospital of Xuzhou Medical University.

The British Journal of Radiology
|June 18, 2026
PubMed
Abstract

No abstract available in PubMed .

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Upon entering the systemic circulation, drugs can distribute into the interstitial and intracellular fluid of various tissue cells. This distribution is facilitated by the binding of drugs to different cellular components within tissues, which may lead to drug accumulation in specific areas. Drugs bound to tissue components serve as reservoirs that release free drugs back into the system, prolonging the drug's overall action. However, this accumulation can also result in local toxicity.
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