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Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...

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In Ovo Feeding of Commercial Broiler Eggs: An Accurate and Reproducible Method to Affect Muscle Development and Growth
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Redox Modulation and Performance Outcomes in Broilers Supplemented with a Phytogenic Anti-Mycotoxin Agent.

Vasileios G Papatsiros1, Zoi Prentza2, Christos Eliopoulos3

  • 1Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, Karditsa, Greece.

Foodborne Pathogens and Disease
|June 18, 2026
PubMed
Summary

A novel phytogenic anti-mycotoxin agent, derived from grape and olive extracts, significantly improved broiler health. The treatment reduced mycotoxin exposure and enhanced the birds' antioxidant capacity, positively impacting overall performance.

Keywords:
broilermycotoxinoxidative stressprotein carbonylstenuazonic acidthiobarbituric acid reactive substancestotal antioxidant capacity

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Area of Science:

  • Animal Science
  • Toxicology
  • Biochemistry

Background:

  • Mycotoxins pose a significant threat to poultry health and performance.
  • Phytogenic compounds offer a natural alternative for mitigating mycotoxin effects.
  • Oxidative stress is a key indicator of mycotoxin-induced damage in broilers.

Purpose of the Study:

  • To evaluate the efficacy of a phytogenic liquid anti-mycotoxin agent on broiler redox status, health, and performance.
  • To assess the impact of grape and olive extracts on mycotoxin exposure and oxidative stress markers.
  • To determine the effects on key physiological and biochemical parameters in broilers.

Main Methods:

  • A large-scale broiler study comparing a control group (22,950 birds) with a treatment group (23,256 birds).
  • Administration of a phytogenic agent in drinking water during critical growth phases.
  • Analysis of liver samples for fungal metabolites using liquid chromatography-tandem mass spectrometry.
  • Measurement of plasma biomarkers including TBARS, CARBs, TAC, total protein, and liver enzymes.

Main Results:

  • The treatment group exhibited an 83% reduction in tenuazonic acid exposure compared to the control.
  • Significant decreases in oxidative stress markers (TBARS, CARBs) and liver enzymes were observed in the treated group.
  • Increased total antioxidant capacity (TAC) and improved growth performance were noted in broilers receiving the phytogenic agent.
  • No significant difference in mortality rates between the groups.

Conclusions:

  • The phytogenic-based anti-mycotoxin agent effectively manages mycotoxin exposure in broilers.
  • Administration of grape and olive extracts positively modulates redox status and enhances broiler health.
  • This natural agent presents a promising strategy for improving poultry production sustainability.