Redox Modulation and Performance Outcomes in Broilers Supplemented with a Phytogenic Anti-Mycotoxin Agent

Area of Science:

• Animal Science
• Toxicology
• Biochemistry

Background:

• Mycotoxins pose a significant threat to poultry health and performance.
• Phytogenic compounds offer a natural alternative for mitigating mycotoxin effects.
• Oxidative stress is a key indicator of mycotoxin-induced damage in broilers.

Purpose of the Study:

• To evaluate the efficacy of a phytogenic liquid anti-mycotoxin agent on broiler redox status, health, and performance.
• To assess the impact of grape and olive extracts on mycotoxin exposure and oxidative stress markers.
• To determine the effects on key physiological and biochemical parameters in broilers.

Main Methods:

• A large-scale broiler study comparing a control group (22,950 birds) with a treatment group (23,256 birds).
• Administration of a phytogenic agent in drinking water during critical growth phases.
• Analysis of liver samples for fungal metabolites using liquid chromatography-tandem mass spectrometry.
• Measurement of plasma biomarkers including TBARS, CARBs, TAC, total protein, and liver enzymes.

Main Results:

• The treatment group exhibited an 83% reduction in tenuazonic acid exposure compared to the control.
• Significant decreases in oxidative stress markers (TBARS, CARBs) and liver enzymes were observed in the treated group.
• Increased total antioxidant capacity (TAC) and improved growth performance were noted in broilers receiving the phytogenic agent.
• No significant difference in mortality rates between the groups.

Conclusions:

• The phytogenic-based anti-mycotoxin agent effectively manages mycotoxin exposure in broilers.
• Administration of grape and olive extracts positively modulates redox status and enhances broiler health.
• This natural agent presents a promising strategy for improving poultry production sustainability.