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[Modern morphological concepts of periprosthetic joint infection in traumatology and orthopedics]
G Yu Kudryavtsev1,2, Ya Yu Kudryavtseva1, V V Labis3
1Peoples' Friendship University of Russia named after Patrice Lumumba, Moscow, Russia.
With the increase in the number of orthopedic surgeries, such as knee and hip replacement, the risk of peri-implant infection also increases. According to various registries, the number of such interventions continues to grow, making the problem of infections particularly relevant. Morphological assessment of peri-implant tissues, primarily the peri-implant membrane, has become routine practice and is used as one of the diagnostic criteria for infection. This review summarizes the main morphological changes in the peri-implant membrane formed at the bone/implant interface, presents the pathogenetic mechanisms of peri-implant osteolysis, and shows the main mechanisms of microorganism persistence in peri-implant infection.
With the increase in the number of orthopedic surgeries, such as knee and hip replacement, the risk of peri-implant infection also increases. According to various registries, the number of such interventions continues to grow, making the problem of infections particularly relevant. Morphological assessment of peri-implant tissues, primarily the peri-implant membrane, has become routine practice and is used as one of the diagnostic criteria for infection. This review summarizes the main morphological changes in the peri-implant membrane formed at the bone/implant interface, presents the pathogenetic mechanisms of peri-implant osteolysis, and shows the main mechanisms of microorganism persistence in peri-implant infection.
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