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Digital Intervention for Electronic Patient-Reported Outcomes in Advanced Cancer: Mixed Methods Study
Christina Sauer1, Simeon Sauer2, Elena Sophia Doll3
1University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, Frankfurt, Hesse, 60590, Germany, 49 69-6301-83787, 49 69-6301-83788.
JMIR Cancer
|June 18, 2026
Summary
This pilot study found that the SOFIA digital health app was feasible and well-accepted by cancer patients. Key features for future digital interventions include intuitive design and physician engagement for improved patient outcomes.
Area of Science:
- Digital health interventions in oncology
- Patient-reported outcomes
- Cancer care technology
Background:
- Digital health tools are increasingly used in cancer care to manage symptoms and distress.
- The SOFIA app, featuring electronic patient-reported outcome (ePRO) assessment and coaching, was tested in a pilot randomized controlled trial.
- The app demonstrated good feasibility and high acceptability in routine clinical settings.
Purpose of the Study:
- To evaluate user experiences and behavior with the SOFIA digital health app.
- To gather insights for refining digital health interventions for cancer patients.
- To improve patient needs, preferences, and engagement with digital health tools.
Main Methods:
- A mixed methods design combining qualitative interviews and quantitative app usage analysis.
- Semistructured interviews were conducted with patients at 6 and 12 weeks.
- Qualitative data were analyzed using content analysis; quantitative data were analyzed using Python and Pandas.
Main Results:
- Qualitative feedback highlighted ePRO benefits (empowerment, communication) and coaching tool advantages (information, design).
- Criticism included inflexible design and insufficient physician use.
- Quantitative data showed 50% read articles, 87.5% started journeys, and 46.9% completed exercises.
Conclusions:
- Digital interventions for cancer patients should prioritize intuitive design, actionable ePRO insights, and physician engagement.
- Therapy-specific content is crucial for increasing acceptance and clinical benefit.
- Findings inform the development of more effective digital health tools for oncology care.