Related Experiment Video
Updated: Jun 20, 2026
12:28
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
Published on: June 3, 2020
Promoting Brain Health in the Context of Normal Aging and Mild Cognitive Impairment: A Tutorial
Matthew L Cohen1,2, Alyssa M Lanzi1,2, Aaron Rothbart3
1Department of Communication Sciences and Disorders, University of Delaware, Newark.
American Journal of Speech-Language Pathology
|June 18, 2026
Summary
Speech-language pathologists (SLPs) can significantly aid in preventing Alzheimer's disease and related dementias (ADRD). Early intervention and promoting brain health across the lifespan offer positive outcomes for individuals and society.
Area of Science:
- Interdisciplinary research in cognitive aging and dementia prevention.
Background:
- Alzheimer's disease and related dementias (ADRD) present significant public health challenges.
- Cognitive aging and brain health are influenced by modifiable risk factors.
- Historically, discussions on cognitive aging and dementia have been stigmatized.
Purpose of the Study:
- To support speech-language pathologists (SLPs) in primary and secondary prevention of ADRD.
- To foster interprofessional collaboration between SLPs and neuropsychologists.
- To provide an evidence-based overview for SLPs on promoting brain health.
Main Methods:
- Synthesis of interdisciplinary literature.
- Inclusion of research on cognitive aging, ADRD, public health, clinical psychology, speech-language pathology, and motivational interviewing.
Main Results:
- An overview of cognitive aging and ADRD.
- Identification of modifiable aspects of brain health.
- Practical strategies for promoting brain health in middle-aged and older adults.
Conclusions:
- Forty-five percent or more of dementia cases may be delayed or prevented through lifestyle modifications.
- Brain health and resilience can be enhanced at any age.
- SLPs and neuropsychologists must collaborate to raise awareness, advocate for services, and motivate clients for brain health improvement.
Related Concept Videos
01:30Cognitive Development During Adulthood
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
01:29Alzheimer Disease l: Introduction
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
01:22Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
01:26Alzheimer's Disease: Overview
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function. They...
01:30Dementia
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
The progression of dementia is generally gradual.