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Tracking mobilization uncovers an evolutionarily conserved mechanism in suppressing mobile genetic elements

Yi Ni Luo1, Yu Liang2, Shuheng Wu2

  • 1State Key Laboratory of RNA Innovation, Science and Engineering, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.

Molecular Cell
|June 18, 2026
PubMed
Summary

A newly identified mechanism suppresses mobile DNA elements called transposons during development. This process, involving Cramp1 and histone H1, prevents genome instability and associated diseases.

Keywords:
Cramp1H3K36me2H3K9me3heterochromatinlinker histone H1transposon

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