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Related Experiment Video

Updated: Jun 20, 2026

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
10:41

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

Published on: November 7, 2017

A modular, high-bandwidth, bidirectional implantable device for neural interrogation.

Radu Darie1, Samuel R Parker2, Jonathan S Calvert1

  • 1Brown University School of Engineering, 184 Hope St, Providence, Rhode Island, 02912, United States.

Journal of Neural Engineering
|June 18, 2026
PubMed
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This summary is machine-generated.

We developed a Modular Bionic Interface (MBI) for high-bandwidth, bidirectional neural recording and stimulation. This fully implantable system offers flexible, modular connections to third-party devices, advancing neuroelectronic interfaces for research and clinical use.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Medical Devices

Background:

  • Current neuroelectronic interfaces are often tethered, limiting mobility and clinical translation.
  • Existing fully implantable systems have constraints like limited modularity or bandwidth.
  • There is a need for flexible, high-bandwidth neuroelectronic interfaces for research and clinical applications.

Purpose of the Study:

  • To develop a fully implantable, modular neuroelectronic interface for high-bandwidth, bidirectional neural interfacing.
  • To create a system compatible with various third-party neural probes.
  • To overcome limitations of current neuroelectronic interface systems.

Main Methods:

  • Development of the Modular Bionic Interface (MBI) system, comprising an implantable device and a wearable unit.
Keywords:
Brain–Computer InterfaceElectrophysiologyNeuromodulationWireless Neural Interfaces

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Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
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Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

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Last Updated: Jun 20, 2026

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
10:41

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

Published on: November 7, 2017

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals
08:26

Surgical Implantation of Chronic Neural Electrodes for Recording Single Unit Activity and Electrocorticographic Signals

Published on: February 24, 2012

  • MBI enables high-fidelity electrophysiological signal recording and spatiotemporally modulated electrical stimulation.
  • Flexible integration with third-party implantable devices for enhanced functionality.

    • Main Results:

    • Benchtop validation confirmed MBI's recording and stimulation capabilities across diverse inputs/outputs.
    • In vivo evaluation in a sheep model showed stable performance for over six months.
    • The MBI system successfully evoked motor responses and recorded spinal compound action potentials when connected to a third-party spinal cord stimulation array.

    Conclusions:

    • A fully implantable, modular neuroelectronic interface with high-resolution, bidirectional communication capabilities has been demonstrated.
    • The MBI system's modular design facilitates flexible connections with third-party devices.
    • This technology is expected to enhance the treatment of complex neurological diseases and injuries.