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Related Experiment Video

Updated: Jun 20, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

Developing a core outcome set for intervention studies in post stroke cognitive impairment (COS-PSCI): a protocol.

Sinead Purcell1,2,3, Katie Robinson4,2,3,5, Margaret O'Connor3,6,7

  • 1School of Allied Health, Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland purcell.sinead@ul.ie.

BMJ Open
|June 18, 2026
PubMed
Summary

Related Concept Videos

Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.

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This study will develop a standardized Core Outcome Set for Post-Stroke Cognitive Impairment (COS-PSCI) to improve research comparability and clinical translation for stroke survivors. The COS-PSCI will enhance outcome measurement consistency in intervention studies.

Area of Science:

  • Neurology
  • Clinical Research Methodology
  • Rehabilitation Science

Background:

  • Post-stroke cognitive impairment (PSCI) significantly affects stroke survivors' quality of life and independence.
  • Current cognitive assessment and intervention research for PSCI lack standardized outcome measures, hindering comparability and clinical translation.
  • A Core Outcome Set (COS) for PSCI is needed to standardize outcome measurement in intervention studies.

Purpose of the Study:

  • To develop a Core Outcome Set for Post-Stroke Cognitive Impairment (COS-PSCI) specifically for intervention research.
  • To establish consensus on essential outcomes and measurement instruments for PSCI research.

Main Methods:

  • The study follows the COS-STAD framework, involving a scoping review, qualitative evidence synthesis, and focus groups.
Keywords:
CognitionDelphi TechniqueStrokeTreatment Outcome

Related Experiment Videos

Last Updated: Jun 20, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

  • A modified eDelphi survey and international consensus meetings will prioritize outcomes and select measurement instruments (guided by COSMIN).
  • Patient and public involvement is integrated throughout the six-stage development process.

    • Main Results:

    • The study is in the development phase and has not yet produced results.
    • The planned methodology will yield a consensus-driven COS-PSCI.

    Conclusions:

    • The development of a COS-PSCI is crucial for standardizing outcome measurement in post-stroke cognitive impairment research.
    • This standardized approach will enhance the comparability of intervention studies and facilitate the translation of research findings into clinical practice.