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USP9X regulates copper-induced CASP9/CASP3/GSDME-dependent pyroptosis by deubiquitinating JAK1

Huaduan Zi1,2,3,4, Hengcheng Tang1,2,3, Xiaoxi Yang1,5

  • 1Laboratory of Molecular Biology, Beijing Institute of Clinical Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

Apoptosis : an International Journal on Programmed Cell Death
|June 18, 2026
PubMed
Abstract

Keywords:
Copper toxicityGSDME-dependent pyroptosisInflammatory injuryJAK1/STAT1 pathwayUSP9X

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