Related Experiment Video
Updated: Jun 20, 2026

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders
Published on: February 3, 2021
A Patient and Physician Perspective of Chronic Coronary Syndrome and Persistent Stable Angina in Brazil
Antônio Figueiredo Araújo1, Aparecida de Fátima Machado Tavares1, Luís Henrique Wolff Gowdak2
1Patient authors, São Paulo, Brazil.
Insights
Chronic coronary syndrome (CCS) causes angina, a challenging condition. Patient experiences highlight gender-based diagnosis and treatment disparities, emphasizing the need for improved awareness and care for myocardial ischemia.
Area of Science:
- Cardiology
- Patient Experience
- Health Disparities
Background:
- Chronic coronary syndrome (CCS) presents with angina, often involving complex patient journeys.
- Diagnosis and treatment of angina can differ significantly between men and women.
- Misconceptions about heart disease predominantly affecting men can delay care for women.
Purpose of the Study:
- To illustrate the challenges and uncertainties in the patient journey with angina.
- To highlight potential gender-based differences in angina diagnosis and treatment.
- To emphasize the importance of accurate diagnosis and optimized management for angina patients.
Main Methods:
- Co-authored article by two patients with stable angina and their cardiologist.
- Patients share over 20 years of personal experiences with angina symptoms, diagnosis, and treatment.
- Cardiologist provides insights into diagnostic challenges, treatment optimization, and gender-related disparities.
Main Results:
- Patients describe a prolonged journey from symptom onset to correct diagnosis and interventions.
- Experiences reveal the significant impact of angina on daily life and physical capacity.
- The cardiologist discusses diagnostic difficulties, including angina with myocardial ischemia but without obstructive coronary artery disease.
Conclusions:
- There is a critical need to raise awareness about angina and its varied presentations among healthcare professionals and the public.
- Addressing gender bias in heart disease diagnosis and treatment is crucial for equitable patient care.
- Optimizing patient assessment and medical treatment is essential for improving quality of life for individuals with angina.
Abstract:
Obstructions in the coronary arteries, arterial vasospasm, and microcirculation dysfunction may cause chronic coronary syndrome (CCS). Angina is a cardinal symptom of CCS and the journey of patients with angina is often filled with challenges and uncertainties. Diagnosis and treatment differences seem to vary between men and women with angina. This article is co-authored by a male and a female patient diagnosed with persistent stable angina and their treating cardiologist at the Heart Institute in São Paulo, Brazil. The patients share their personal experiences of more than 20 years of coping with pain and the related impact on their physical capacity, thus illustrating the challenging journey often faced by individuals with angina and how it differs between men and women. They describe the long pathway from the onset of symptoms to the correct diagnosis and list the various interventional procedures they underwent, focusing on the impact of angina on their daily lives. They also mention their participation in a clinical study. The cardiologist discusses the critical elements in the diagnostic process of angina, and reflects on how the misconception that heart disease primarily affects men can lead to delayed diagnosis and treatment for women suffering from this condition. Moreover, he emphasizes that many patients experience angina due to myocardial ischemia without obstructive coronary artery disease, highlighting the need to raise disease awareness among healthcare professionals, as well as in society. Finally, the physician underscores the importance of better patient assessment and medical treatment optimization to managing angina and meeting patients' needs and expectations, while prioritizing patient quality of life.
Related Concept Videos
Angina III: Clinical Manifestations and Assessment
Angina V: Nursing Management
Angina IV: Management
Angina II: Classification
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease V: Interprofessional Care

