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Updated: Jun 20, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Catalyst-Free Selective Reduction of Nitrogen Dioxide to Nitric Oxide
Awais W Seyyad1, Agamemnon E Crumpton1, Reece Lister-Roberts1
1Department of Chemistry, University of Oxford, Oxford, UK.
None:
Nitrogen dioxide (NO2) is a highly toxic gas and a notorious respiratory irritant that contributes to the greenhouse effect and acid rain. Herein, we study the catalyst-free reduction of NO2 with boranes, silanes, and the hydrogen surrogates 1,4-cyclohexadiene and isopropyl alcohol, resulting in the selective formation of nitric oxide (NO). Selective NO generation was confirmed by electron paramagnetic resonance spectroscopy and low-temperature 15N{1H} nuclear magnetic resonance spectroscopy. Additionally, density functional theory calculations have been employed to probe the mechanism of these reductions.
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