Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metabolic footprint of sepsis and septic shock: A narrative review.

World journal of critical care medicine·2026
Same author

Synthesis, structural characterization, and electrocatalytic hydrogen generation activity of <i>fac</i>-tris(β-oxodithioester-O^S)cobalt(III) complexes.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Advancement in Sodium Alginate-Based Drug Delivery Systems: Applications and Future Prospects.

AAPS PharmSciTech·2026
Same author

Translational advances of exosomes in neurodegeneration towards precision healthcare: From biomarkers to therapeutic frontiers.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Corneal Targeted Mucoadhesive Emulsion for Prolonged Delivery of Voriconazole: Formulation Evaluation and Pharmacokinetic Assessment.

Biopharmaceutics & drug disposition·2026
Same author

Prospective Evaluation of Surgical Ergonomics Among Endocrine Surgeons in Open Thyroidectomy: A Pilot Study.

Head & neck·2026

Related Experiment Video

Updated: Jun 20, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Bone Health in Breast Cancer Patients: Comparative Evaluation Using Dual Energy X-Ray Absorptiometry Scan and

Sunaina Kumari1, Sabaretnam Mayilvaganan2, Sushil Gupta3

  • 1Department of Endocrine and Breast Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Journal of Bone Metabolism
|June 19, 2026
PubMed
Summary

High-resolution peripheral quantitative computed tomography (HR-pQCT) better detects bone microarchitecture deterioration in Indian women with breast cancer than dual energy X-ray absorptiometry (DXA). This finding highlights HR-pQCT

Keywords:
Bone microarchitectureBone mineral densityHR-pQCTOsteoporosis

More Related Videos

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis
08:04

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Related Experiment Videos

Last Updated: Jun 20, 2026

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis
08:04

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Area of Science:

  • Oncology
  • Radiology
  • Bone Metabolism

Background:

  • Osteoporosis is common in Indian women, worsened by cancer therapies like chemotherapy and hormonal therapy.
  • Breast cancer patients are highly susceptible to bone loss, with standard dual energy X-ray absorptiometry (DXA) lacking microarchitecture assessment.
  • High-resolution peripheral quantitative computed tomography (HR-pQCT) offers potential for detailed bone microarchitecture evaluation.

Purpose of the Study:

  • To compare the efficacy of HR-pQCT versus DXA in assessing bone health in Indian women with breast cancer.
  • To evaluate bone density and microarchitecture using both DXA and HR-pQCT in this patient cohort.

Main Methods:

  • A cross-sectional pilot study involving 54 Indian women with breast cancer (no bone metastases) was conducted.
  • Data collected included demographics, clinical details, and cancer treatment history.
  • Bone density and microarchitecture were assessed using both DXA and HR-pQCT, followed by statistical analysis.

Main Results:

  • Osteoporosis and osteopenia were prevalent (38.2% and 61.8%, respectively) by DXA.
  • HR-pQCT showed significantly lower volumetric bone density (P<0.01) and revealed microarchitectural deficits.
  • Deficits were pronounced in postmenopausal women, chemotherapy recipients, and those on letrozole, with poor DXA-HR-pQCT agreement.

Conclusions:

  • HR-pQCT demonstrates superiority over DXA in identifying bone microarchitectural deterioration in breast cancer patients.
  • This pilot study underscores the need for larger prospective research on Indian populations.
  • HR-pQCT may offer a more comprehensive assessment of bone health in cancer patients.