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Updated: Jun 20, 2026

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
09:38

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

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Challenges in Implementing Revocation of Oncology Drugs Under Conditional Early Approval in Japan: Regulatory

Takahiro Handa1,2, Arata Tanaka3, Mayumi Shikano1,3

  • 1Graduate School of Pharmaceutical Sciences, Tokyo University of Science, Tokyo, Japan.

Clinical and Translational Science
|June 19, 2026
PubMed
Abstract

Keywords:
FDAdrug developmentoncologypatientspublic policyregulatory

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