Grisotti versus Wise-Pattern Oncoplastic Reconstruction in Central Breast Cancer: A Randomized Controlled Study

Area of Science:

• Oncoplastic surgery
• Breast reconstruction
• Surgical oncology

Background:

• Central breast tumors requiring nipple-areola complex excision pose a reconstructive challenge in breast-conserving surgery.
• Volume-displacement oncoplastic techniques aim to preserve the breast while ensuring oncological safety.
• The Grisotti flap and Wise-pattern reconstruction are two such techniques.

Purpose of the Study:

• To compare the short-term oncological and aesthetic outcomes of the Grisotti flap versus Wise-pattern reconstruction for central breast tumors.
• To evaluate surgical margin status, postoperative complications, and patient/surgeon satisfaction.

Main Methods:

• A randomized controlled trial involving 40 patients with central breast cancer.
• Patients were randomized to either the Grisotti technique (n=20) or the Wise-pattern technique (n=20).
• Outcomes assessed included surgical margins, complications, and aesthetic satisfaction over a mean follow-up of 6.9 months.

Main Results:

• Both techniques achieved high rates of negative surgical margins (90% Grisotti, 100% Wise-pattern).
• Postoperative complications were similar between groups, with seroma being the most common.
• Patient satisfaction was high for both (85% Grisotti, 90% Wise-pattern), with no significant difference in surgeon satisfaction.

Conclusions:

• The Grisotti and Wise-pattern techniques provide comparable short-term oncological safety and aesthetic outcomes for central breast tumors.
• Individualized selection based on breast volume and ptosis is recommended.
• Larger studies with longer follow-up are needed to assess long-term results.