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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
Published on: February 1, 2022
Association Between Right Ventricular Dysfunction and Coronary Angiographic Complexity in Patients With Acute
Kazi Mohammad Faisal1, Asish Dey2, Md Nur Uddin Tareq1
1Department of Cardiology, Chittagong Medical College Hospital, Chattogram, BGD.
Cureus
|June 19, 2026
Summary
Right ventricular dysfunction (RVD) is linked to more complex coronary angiograms in acute myocardial infarction (AMI) patients. This finding suggests RVD may aid in early risk stratification for AMI, guiding treatment decisions.
Area of Science:
- Cardiology
- Echocardiography
- Interventional Cardiology
Background:
- Acute myocardial infarction (AMI) is a leading cause of death globally.
- Right ventricular dysfunction (RVD) impacts AMI outcomes but its link to coronary complexity is unclear.
Purpose of the Study:
- To investigate the association between RVD and coronary angiographic complexity in AMI patients.
- To explore RVD as a potential marker for risk stratification in AMI.
Main Methods:
- Prospective observational study of 98 AMI patients.
- Echocardiography assessed RVD (TAPSE, S' velocity, FAC).
- Coronary angiographic complexity measured by SYNTAX score.
Main Results:
- RVD was significantly associated with intermediate and high SYNTAX scores (p=0.002).
- Patients with RVD had lower systolic blood pressure, TAPSE, and FAC.
- Multivariable analysis showed RVD independently predicted higher SYNTAX scores (OR=7.86).
Conclusions:
- RVD is significantly associated with greater coronary angiographic complexity in AMI.
- RVD may serve as a valuable noninvasive marker for early risk stratification in AMI patients.
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