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Related Experiment Video

Updated: Jun 20, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Peripheral nerve stimulation - Our experiences with the wireless high-frequency system.

U M Bäzner1, L Minzenmay1, C R Wirtz1

  • 1Department of Neurosurgery, University of Ulm, Bezirkskrankenhaus, Günzburg.

Brain & Spine
|June 19, 2026
PubMed
Summary
This summary is machine-generated.

Wireless peripheral nerve stimulation (PNS) effectively reduced chronic pain and medication use in 81% of patients. This minimally invasive approach offers a safe alternative for managing neuropathic pain, with 90.5% willing to undergo the procedure again.

Keywords:
NeuromodulationPainPeripheral nerve surgeryUltrasound-guided

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Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning
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Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning

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The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

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Related Experiment Videos

Last Updated: Jun 20, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning
14:47

Combined Peripheral Nerve Stimulation and Controllable Pulse Parameter Transcranial Magnetic Stimulation to Probe Sensorimotor Control and Learning

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The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
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The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

Published on: January 13, 2022

Area of Science:

  • Neurology
  • Pain Management
  • Minimally Invasive Procedures

Background:

  • Chronic pain syndromes significantly impact quality of life.
  • Traditional neurostimulator implantation carries risks.
  • Wireless high-frequency peripheral nerve stimulation (PNS) presents a less invasive alternative.

Purpose of the Study:

  • To evaluate the efficacy and safety of wireless high-frequency PNS for chronic pain.
  • To assess pain reduction, medication usage, and patient satisfaction.

Main Methods:

  • 21 patients with chronic neuropathic pain received wireless high-frequency PNS.
  • Implantation was performed under local anesthesia with ultrasound guidance.
  • Targeted nerves included ulnar, peroneal, tibial, and median nerves.

Main Results:

  • 81% of patients experienced significant pain reduction (NRS scores decreased from 8.2 to 4.3).
  • 66.7% reduced or discontinued pain medication.
  • No complications were reported; 90.5% would choose PNS again.

Conclusions:

  • Wireless high-frequency PNS is a feasible and effective option for chronic neuropathic pain.
  • The system demonstrates a favorable safety profile with high patient satisfaction.
  • Effectiveness may be reduced in patients with prior partial nerve grafting.