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Published on: June 20, 2014
Ultraviolet light-induced C-C bond cleavage of tert-cycloalkanols using anthraquinone
Hong-Ze Geng1, Xing-Wei Jiang1, Hao Lv1
1College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. China. yuanx@njtech.edu.cn.
Abstract:
Herein, this paper reports a general anthraquinone-photocatalyzed method for selective C-C bond cleavage of cycloalkanols under ambient conditions, enabling site-specific remote sulfonylated ketone synthesis via proton-coupled electron transfer. The reaction shows broad functional-group tolerance and continuous-flow scalability, and provides an efficient route to functionalized ketones.
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