Related Experiment Video

Updated: Jun 20, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
05:35

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Effect of Home-Based Multiple Micronutrient Powder Fortification on Haemoglobin Levels in Infants in Nampula,

Ana Raquel Ernesto Manuel Gotine1,2, Marly Augusto Cardoso3,4

  • 1Postgraduate Program in Public Health, University of São Paulo (USP), São Paulo, São Paulo, Brazil.

Maternal & Child Nutrition
|June 19, 2026
PubMed

Insights

Multiple micronutrient powders (MNPs) significantly improved hemoglobin levels in infants, reducing anemia rates in Mozambique. This study supports MNPs as a key intervention for anemia control in vulnerable populations.

Area of Science:

  • Public Health
  • Pediatrics
  • Nutritional Science

Background:

  • Iron deficiency anemia is a major global health issue affecting infants.
  • Primary care settings offer opportunities for nutritional interventions.
  • Early life nutrition is critical for long-term health outcomes.

Purpose of the Study:

  • To evaluate the effectiveness of multiple micronutrient powders (MNPs) in preventing anemia among infants in Mozambique.
  • To assess the impact of MNPs on hemoglobin levels in the first year of life.
  • To provide evidence for MNP implementation in primary care settings.

Main Methods:

  • A pragmatic clinical trial involving 275 infants aged 6-8 months in Nampula, Mozambique.
  • Random assignment to an intervention group receiving daily MNPs or a control group receiving standard care.
  • Hemoglobin levels measured at baseline and after 6 months, with analysis using adjusted linear regression.

Main Results:

  • The intervention group showed a mean increase in hemoglobin of +2.8 g/L, while the control group had a decrease of -4.3 g/L.
  • Anemia rates decreased from 55.2% to 36% in the MNP group, compared to an increase from 47.7% to 67.3% in the control group.
  • MNPs significantly improved hemoglobin levels and reduced anemia prevalence in infants.

Conclusions:

  • Multiple micronutrient powders are effective in improving hemoglobin levels and preventing anemia in infants.
  • MNPs represent a viable and impactful strategy for anemia control in vulnerable populations within primary care.
  • The findings support the integration of MNPs into routine infant care programs.

Keywords:
anaemiacomplementary feedinghome fortificationiron deficiencymicronutrients

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