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Updated: Jun 20, 2026
06:59
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Hypodermoclysis for Fluid Administration in Hospitalized Pediatric Patients: A Scoping Review
Mariana de Siqueira Silva1, Beatriz Bernava Sarinho1, Thamires Da Silva Feres1
1School of Pharmaceutical Sciences.
Pediatric Emergency Care
|June 19, 2026
Summary
Hypodermoclysis (subcutaneous fluid administration) is a safe and effective method for hydrating pediatric patients, especially those with difficult venous access. This technique improves patient comfort and satisfaction while reducing the need for repeated needle insertions.
Area of Science:
- Pediatric Medicine
- Fluid Management
- Medical Procedures
Background:
- Difficult venous access is a common challenge in pediatric hydration.
- Hypodermoclysis offers an alternative route for fluid administration in children.
- Existing literature on hypodermoclysis in pediatric populations requires synthesis.
Purpose of the Study:
- To conduct a scoping review of hypodermoclysis for fluid administration in neonates, infants, and children up to 12 years old.
- To map the available literature on the use and outcomes of hypodermoclysis in pediatric hospital settings.
Main Methods:
- A comprehensive scoping review was performed using major databases (PubMed, Scopus, Web of Science, CINAHL).
- Studies published between 1950 and 2025 involving hospitalized children (0-12 years) receiving hypodermoclysis were included.
- Article screening was conducted independently by two reviewers.
Main Results:
- Ten studies evaluated hypodermoclysis in emergency, inpatient, and palliative care settings.
- 0.9% sodium chloride was the most common fluid; hyaluronidase was frequently used.
- Hypodermoclysis demonstrated safety with manageable local adverse effects and successful treatment of dehydration.
- The procedure was found to be simple, well-accepted by healthcare professionals, and satisfactory for caregivers.
Conclusions:
- Hypodermoclysis is a safe and effective option for pediatric dehydration.
- Implementing hypodermoclysis in clinical protocols can minimize venipuncture distress and enhance patient/family satisfaction.
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