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Updated: Jun 20, 2026

An In-House-Built and Light-Emitting-Diode-Based Photodynamic Therapy Device for Enhancing Verteporfin Cytotoxicity in a 2D Cell Culture Model
Published on: January 13, 2023
Merkel cell carcinoma following photodynamic therapy in a high-risk patient
Francesca Polita1, Massimiliano Mengarino1, Valentina Carelli1
1Department of Dermatology and Venereology, Hospital of Merano (BZ).
Abstract:
Dear Editor, Merkel cell carcinoma (MCC) is defined as a rare but highly aggressive skin cancer originating from neuroendocrine cells. Clinically, it usually appears as a rapidly growing, solid, asymptomatic, redviolaceous nodule. Its development is primarily associated with the integration of the Merkel cell polyomavirus (MCPyV) and extended exposure to ultraviolet (UV) radiation. The disease predominantly affects older individuals with fair skin. There is an increased incidence of MCC among immunocompromised individuals, such as patients suffering from hematological malignancies. [...].

