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Related Concept Videos

Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Pleura of the Lungs01:13

Pleura of the Lungs

The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

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Related Experiment Video

Updated: Jun 21, 2026

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
07:29

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

Destroyed Lungs and Surgical Management.

Lihui Yu1, Jingyu Chen2,3,4,5

  • 1Wuxi School of Medicine, Jiangnan University, Wuxi, 214122, China.

Pulmonary Therapy
|June 19, 2026
PubMed
Summary
This summary is machine-generated.

Destroyed lung, a severe end-stage condition from chronic infection, involves irreversible lung damage. While pneumonectomy is an option, lung transplantation is reserved for highly selected patients with end-stage disease.

Keywords:
Destroyed lungLung transplantationSurgical management

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Mouse Pneumonectomy Model of Compensatory Lung Growth
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Mouse Pneumonectomy Model of Compensatory Lung Growth

Published on: December 17, 2014

Related Experiment Videos

Last Updated: Jun 21, 2026

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
07:29

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Mouse Pneumonectomy Model of Compensatory Lung Growth
09:22

Mouse Pneumonectomy Model of Compensatory Lung Growth

Published on: December 17, 2014

Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Critical Care Medicine

Background:

  • Destroyed lung is an irreversible end-stage condition of chronic pulmonary infection.
  • It leads to significant parenchymal destruction and functional impairment.
  • Medical management can control infection but not structural damage.

Purpose of the Study:

  • To review the etiologies, clinical manifestations, and surgical management of destroyed lung.
  • To evaluate the role, indications, and challenges of lung transplantation in destroyed lung patients.
  • To compare lung transplantation with conventional surgical options like pneumonectomy.

Main Methods:

  • This is a narrative review.
  • Literature search on destroyed lung, pneumonectomy, and lung transplantation.
  • Synthesis of current evidence and clinical practice.

Main Results:

  • Pneumonectomy is the conventional surgical approach for unilateral destroyed lung but carries risks.
  • Lung transplantation is an option for select patients with end-stage, bilateral, or functionally compromised destroyed lung.
  • Lung transplantation is not a routine substitute for pneumonectomy.

Conclusions:

  • Destroyed lung management requires careful consideration of surgical options.
  • Lung transplantation offers a solution for specific, highly selected patients.
  • Further research is needed to define optimal strategies for destroyed lung treatment.