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Updated: Jun 21, 2026

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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Intestinal deglycosylation activates saikosaponins as potent, selective UGT2B7/2B15 inhibitors: structural basis and

Jinqian Chen1, Peiyao Duan2, Haotian Ma3

  • 1NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|June 20, 2026
PubMed

Keywords:
Radix BupleuriUDP-glucuronosyltransferasesenzyme inhibitionherb-drug interactionsaikosaponin aglycones

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