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Structural basis of ligand selectivity in FAD/NAD(P)H-dependent dehydrogenases: insights from trypanothione reductase

Giulia Chiara Maria Perrone1, Serena Spadone1, Anna Lucia Francavilla2

  • 1Laboratory of Biochemistry, Structural and Molecular Biology, Department of Pharmacy-Pharmaceutical Sciences, University of Bari "Aldo Moro", Bari, Italy.

Protein Science : a Publication of the Protein Society
|June 20, 2026
PubMed

Keywords:
Caldalkalibacillus thermarumFAD/NAD(P)H‐dependent dehydrogenasesLeishmania infantumdocking selectivity analysisdrug repurposingenzyme inhibitionhomology modelingredox metabolismstructure‐based drug designtrypanothione reductase

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