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Related Concept Videos

Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...

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Related Experiment Video

Updated: Jun 23, 2026

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
07:58

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury

Published on: July 17, 2016

Response to Postoperative Acute Kidney Injury: Does Knowledge Equate to Action?

Megan E Boyer1, Anthony Loria1, Bailey K Hilty Chu1

  • 1Department of Surgery, Surgical Health Outcomes Research Enterprise (SHORE), University of Rochester Medical Center, Rochester, New York.

The Journal of Surgical Research
|June 20, 2026
PubMed
Summary

Postoperative acute kidney injury (AKI) management and follow-up are inconsistent and incomplete. Standardized care practices are needed to improve outcomes for patients experiencing AKI after surgery.

Keywords:
AKIAcute kidney injuryNephrotoxicityPerioperative riskRenalSecondary prevention

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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

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Last Updated: Jun 23, 2026

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
07:58

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury

Published on: July 17, 2016

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

Area of Science:

  • Nephrology
  • Surgical Care
  • Critical Care Medicine

Background:

  • Acute kidney injury (AKI) is a common postoperative complication with significant morbidity.
  • Standardized diagnostic criteria for AKI have improved recognition, but management and follow-up remain unclear.

Purpose of the Study:

  • To evaluate the management, documentation, and follow-up practices for postoperative acute kidney injury (AKI).
  • To identify gaps in perioperative renal care.

Main Methods:

  • Retrospective cohort study of adult patients with postoperative AKI at a tertiary medical center.
  • Analysis of AKI management interventions, documentation completeness, and follow-up practices.
  • Secondary outcomes included AKI severity, perioperative exposure, and 30-day mortality.

Main Results:

  • Most patients (93.3%) had stage 2 or 3 AKI; 18.3% required kidney replacement therapy.
  • AKI documented in 63.5% of notes, 38.5% of discharge summaries. Postdischarge nephrology referral occurred in 6.7%.
  • Only 58.7% had postdischarge laboratory follow-up within 30 days; 30-day mortality was 18.3%.

Conclusions:

  • Postoperative AKI management, documentation, and follow-up are frequently incomplete.
  • Significant gaps exist in perioperative renal care.
  • Coordinated, multi-institutional efforts are needed for standardized AKI care practices.