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Chromosome-level assembly and annotation of the Jaguar (Panthera onca) genome
Fernando Cruz1,2, Jèssica Gómez-Garrido1,2, Anna Vlasova3,4
1Centro Nacional de Análisis Genómico (CNAG), Baldiri Reixac 4, Barcelona, 08028, Spain.
Objectives:
The Jaguar (Panthera onca) is a large cat species native to the Americas. Despite being successful predators, jaguar populations have declined due to habitat loss. Genome resources can help in conservation efforts as well as in understanding the interesting biology of these Felids. Beside contiguity, a well annotated reference genome provides contextual information for variants that will benefit the design of appropriate conservation programs.
Data Description:
We sequenced material from two individuals using a combination of ONT reads and Illumina PE. The resulting nuclear genome assembly has a larger contig N50 (48.04 Mb) compared with the existing annotated chromosome-level assembly published by the DNA Zoo project. Using public Hi-C data, we obtained an improved chromosome-level assembly of the Jaguar genome (mPanOnc3.5) with larger contigs, 99.85% of the sequence assigned to chromosomes and 25,267 protein coding genes annotated. Overall, this improved assembly provides a better reference to study this threatened species.
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Chromosome Structure
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
Chromosome Structure
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...

