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Gastro-gastric intussusception in adults: a systematic review with exploratory statistical analysis
Konstantinos Kossenas1, Konstantinos Lasithiotakis2, Stylianos Kykalos3
1Second Propaedeutic Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece. kossenaswork@gmail.com.
Clinical Journal of Gastroenterology
|June 21, 2026
Summary
This review synthesizes evidence on adult gastro-gastric intussusception, a rare condition. It highlights that CT scans are key for diagnosis, and surgery is the primary treatment, predominantly affecting older females with gastrointestinal symptoms.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Radiology
Background:
- Gastro-gastric intussusception is a rare condition in adults with limited, scattered literature.
- Existing research lacks systematic analysis, necessitating a comprehensive review.
Purpose of the Study:
- To systematically review and synthesize current evidence on adult gastro-gastric intussusception.
- To elucidate clinical presentations, diagnostic modalities, and management strategies for this rare condition.
Main Methods:
- Adherence to PRISMA guidelines for an extensive systematic search across multiple databases.
- Inclusion of English literature on adult patients (≥16 years) with confirmed gastro-gastric intussusception.
- Utilisation of descriptive statistics and Chi-square tests for data analysis.
Main Results:
- Forty-three cases were analyzed, predominantly affecting older females (77%) with gastrointestinal symptoms (72.5%).
- Computed tomography (CT) demonstrated 100% diagnostic yield, followed by endoscopy.
- Gastro-intestinal stromal tumors (23.3%) were the most common cause; surgical resection was the primary treatment (58.1%).
Conclusions:
- Adult gastro-gastric intussusception primarily impacts older females, presenting with gastrointestinal symptoms.
- CT is the preferred diagnostic tool, and surgical resection remains the standard treatment.
- Standardized reporting and prospective registries are crucial for optimizing diagnosis and management.
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