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Updated: Jun 29, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

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MTA-Swin: A Multi-Token Attention Swin Transformer for Brain Tumor Classification with Leakage-Free MRI Benchmarking.

Dong Lu1, Yu Zhang1, Divya Chaudhary2

  • 1College of Engineering, Northeastern University, 401 Terry Ave N, Seattle, WA, 98109, United States.

Journal of Medical Systems
|June 21, 2026
PubMed
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This study introduces a method to remove duplicate data in brain tumor MRI datasets, creating a reliable benchmark. A new model, MTA-Swin, achieves 98.57% accuracy in brain tumor classification, offering a practical diagnostic tool.

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computer Vision

Background:

  • Accurate brain tumor classification is crucial for patient diagnosis and treatment.
  • Magnetic resonance imaging (MRI) is vital for early detection.
  • Existing MRI datasets often contain duplicates, leading to unreliable deep learning model evaluations.

Purpose of the Study:

  • To address data leakage in brain tumor MRI datasets caused by duplicates.
  • To develop an automated pipeline for identifying and removing duplicate scans.
  • To propose and evaluate an enhanced deep learning model for improved brain tumor classification.

Main Methods:

  • Systematic analysis of duplicate-induced data leakage in MRI datasets.
  • Development of an automated data cleaning pipeline.
Keywords:
Brain tumor classificationComputer visionData leakageDeep learningMedical imagingMulti-Token attentionSwin transformer

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  • Creation of a leakage-free benchmark dataset (3,522 unique scans).
  • Proposal of MTA-Swin, a Swin Transformer with Multi-Token Attention.
  • Pre-training MTA-Swin on ImageNet-1K and fine-tuning on the cleaned dataset.
  • Main Results:

    • A leakage-free benchmark dataset was established.
    • MTA-Swin achieved 98.57% overall accuracy across three random seeds.
    • The model outperformed thirteen baseline methods.
    • Stratified cross-validation and Grad-CAM analyses confirmed robustness and interpretability.

    Conclusions:

    • Automated data cleaning is essential for reliable brain tumor MRI dataset evaluation.
    • MTA-Swin demonstrates superior performance in brain tumor classification.
    • The proposed model shows potential as a practical computer-aided diagnostic support system.