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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Related Experiment Video

Updated: Jun 23, 2026

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8⁺ T Cells in Mice

Published on: June 12, 2021

Intestinal transplantation for tumors.

Cal S Matsumoto¹, Sukanya Subramanian

¹Medstar Georgetown Transplant Institute, Washington, District of Columbia, USA.

Current Opinion in Organ Transplantation

|June 22, 2026

Summary

This summary is machine-generated.

Intestinal transplantation offers excellent survival for specific abdominal tumors like desmoid tumors. Early referral and careful patient selection are crucial for successful outcomes in these complex cases.

Keywords:

desmoid tumor intestine transplant multivisceral transplant neuroendocrine tumor pseudomyxoma peritonei

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Last Updated: Jun 23, 2026

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

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Published on: June 12, 2021

Small Bowel Transplantation In Mice

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Published on: August 20, 2007

Successful Orthotopic Liver Transplantation in Mice Utilizing Microcomputed Tomography Angiography

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Published on: September 22, 2023

Area of Science:

Gastroenterology
Surgical Oncology
Transplant Surgery

Background:

Intestinal transplantation is a critical treatment for various intra-abdominal tumors.
Reviewing current practices and outcomes is essential for optimizing patient care.

Purpose of the Study:

To provide a comprehensive review of current practices and outcomes of intestinal transplantation for intra-abdominal tumors.
To highlight the role of intestinal transplantation in managing specific oncological conditions.

Main Methods:

Comprehensive literature review of intestinal transplantation for intra-abdominal tumors.
Analysis of survival outcomes, indications, and patient selection criteria.

Main Results:

Intestinal transplantation demonstrates excellent survival for intra-abdominal desmoid tumors, especially aggressive forms associated with familial adenomatous polyposis syndrome.
Acceptable survival and recurrence outcomes are achievable for carefully selected patients with metastatic neuroendocrine tumors and pseudomyxoma peritonei.
It is also an option for patients with intestinal failure post-abdominal malignancy resection.

Conclusions:

Intestinal transplantation is a viable therapeutic option for selected patients with intra-abdominal desmoid tumors, neuroendocrine tumors, and pseudomyxoma peritonei.
Successful long-term outcomes depend on meticulous patient selection, surgical expertise, and vigilant post-transplant oncologic surveillance.