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Updated: Jun 23, 2026

Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis
07:10

Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis

Published on: July 8, 2025

Correction: Development of a highly sensitive fluorescent light-up probe for G-quadruplexes

Ming-Hao Hu1, Shuo-Bin Chen1, Rui-Jun Guo1

  • 1School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China. tanjiah@mail.sysu.edu.cn.

The Analyst
|June 22, 2026
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...