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Updated: Jun 23, 2026

Flow Cytometry-Based Isolation and Therapeutic Evaluation of Tumor-Infiltrating Lymphocytes in a Mouse Model of Pancreatic Cancer
Published on: January 17, 2025
IL1RAP-expressing myeloid-stromal networks represent a therapeutic vulnerability to improve chemoimmunotherapy
Erin M Dickey1, Harper M Marsh1, Camilla Rydberg-Millrud2
1Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, USA.
Abstract:
IL1RAP blockade remodels the pancreatic cancer microenvironment, reduces myeloid immunosuppression, restores memory-like CD8+ T cell states, and enhances chemoimmunotherapy sensitivity.
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