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Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...

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Related Experiment Videos

Severe Sepsis After Vaginal Delivery: A Case Report.

Maryam Dehghan1

  • 1Obstetrician and Gynecologist, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran, mui.ac.ir.

Case Reports in Obstetrics and Gynecology
|June 22, 2026
PubMed
Summary

Severe postpartum sepsis, a significant cause of maternal mortality, requires prompt recognition and intervention. Surgical source control can be lifesaving in severe cases unresponsive to antibiotics, even after vaginal delivery.

Keywords:
hysterectomymaternal morbiditypostpartum sepsisseptic shocksource control

Related Experiment Videos

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • Postpartum sepsis is a major contributor to maternal morbidity and mortality globally.
  • Early identification and prompt intervention are crucial for improving patient outcomes.
  • Risk factors like malnutrition and low socioeconomic status can exacerbate sepsis severity.

Purpose of the Study:

  • To present a case of severe postpartum sepsis with multiple organ involvement.
  • To emphasize the role of multidisciplinary management and surgical source control.

Main Methods:

  • Case report of a 29-year-old woman with severe postpartum sepsis following preterm delivery.
  • Management included broad-spectrum antibiotics, fluid resuscitation, and ultimately, surgical intervention (hysterectomy, salpingectomy, chest tube insertion).

Main Results:

  • The patient developed refractory septic shock with methicillin-resistant Staphylococcus aureus (MRSA) infection.
  • Surgical source control was necessary due to unresponsiveness to medical management.
  • Postoperative recovery and discharge were achieved 14 days after surgery.

Conclusions:

  • Early recognition and aggressive management are vital for high-risk postpartum patients.
  • Multidisciplinary care and timely surgical intervention can be lifesaving.
  • Surgical source control is a critical option for postpartum sepsis refractory to medical therapy.