Related Experiment Videos
Tumor-Related Pericardial and Myocardial Infiltration in Diffuse Large B-Cell Lymphoma Presenting as an ST-Elevation
Zhandos Burkitbayev1, Ainur Bilmakhanbetova1,2, Aliya Omarbek1,2
1National Research Oncology Center, Astana, Kazakhstan.
Background:
Cardiac involvement in diffuse large B-cell lymphoma (DLBCL) is rare and often underrecognized. Concurrent pericardial and myocardial infiltration can mimic acute myocardial infarction on electrocardiography, posing diagnostic challenges.
Case Presentation:
We present a 64-year-old female with biopsy-confirmed DLBCL who developed acute respiratory symptoms and electrocardiographic changes mimicking ST-elevation myocardial infarction (STEMI). Multimodal imaging revealed a large pericardial effusion, myocardial infiltration, and no obstructive coronary disease. Despite chemotherapy and supportive care, the patient succumbed to cardiopulmonary failure.
Conclusion:
This case highlights a rare manifestation of lymphoma-associated cardio-infiltration presenting as STEMI mimic. Early multidisciplinary evaluation is essential to differentiate pseudo-infarction syndromes and prevent unnecessary invasive interventions.
Related Concept Videos
Myocarditis II: Clinical Features and Diagnostic Tests
Pericarditis II: Clinical Features and Diagnostic Tests
Myocarditis I: Introduction
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy
Cardiomyopathy I: Introduction and Classification