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Updated: Jun 23, 2026

A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
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The Gut-Disc Axis: Mendelian Randomization Study Reveals Causal Effects of Gut Microbiota on Intervertebral Disc

Ziqiao Yan1, Qiang Jiang1, Zhengcao Lu1

  • 1Department of Orthopaedics, Senior Department of Traditional Chinese Medicine, The Sixth Medical Center of PLA General Hospital, Beijing, People's Republic of China.

International Journal of General Medicine
|June 22, 2026
PubMed
Abstract

Keywords:
Mendelian randomizationcausalitygut microbiotainflammatory cytokinesintervertebral disc degenerationmediation analysis

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