Geniculate Artery Embolization for Recurrent Effusion After Total Knee Arthroplasty in a Patient With Hemophilia

Miranda Czymek1, Rex W Lutz2, Christopher Kim3

  • 1Orthopedics, Rowan-Virtua School of Osteopathic Medicine, Stratford, USA.

Cureus
|June 22, 2026
PubMed

Treatment options are limited in those with end-stage hemophilic arthropathy. Total knee arthroplasty (TKA) serves as a therapeutic and definitive treatment for hemophilic arthropathy, yet patients with hemophilia (PWH) are at increased risk of recurrent hemarthrosis following TKA. Standardized treatment of recurrent effusion (RE) after TKA has not been well-established. In this case presentation, a 62-year-old male with hemophilia A presented with RE after TKA for end-stage hemophilic arthropathy. After undergoing conservative management and an infectious workup, the patient was referred to interventional radiology for geniculate artery embolization (GAE). Four arteries near hemostasis were achieved. The patient's outcomes were evaluated using the Western Ontario and McMaster Osteoarthritis Index (WOMAC). At the three-month follow-up from embolization, the patient had an 83% decrease in the WOMAC score and no recurrence of effusion.

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