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Integrative oncology: evolution, framework, and future directions
Lorenzo Cohen1, Eran Ben-Arye2,3,4
1Department of Palliative, Rehabilitation, & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Frontiers in Oncology
|June 22, 2026
Summary
Integrative oncology combines conventional cancer treatments with mind-body practices, natural products, and lifestyle strategies. This patient-centered approach aims to improve wellbeing and quality of life for cancer patients.
Area of Science:
- Integrative oncology research
- Evidence-based cancer care
- Patient-centered treatment models
Background:
- Cancer treatment has evolved beyond tumor-directed modalities.
- Recognizes the interplay of biological, behavioral, psychosocial, and environmental factors in patient outcomes.
- Integrative oncology emerged from patient needs and limitations of purely biomedical frameworks.
Purpose of the Study:
- To outline the historical trajectory and scientific foundations of integrative oncology.
- To describe clinical models and future opportunities in the field.
- To highlight the potential of integrative oncology to transform cancer care.
Main Methods:
- Review of historical development and scientific evidence in integrative oncology.
- Analysis of clinical models and patient-centered approaches.
- Discussion of challenges and future research directions.
Main Results:
- Integrative oncology integrates diverse factors for enhanced patient wellbeing.
- Evidence-based guidelines and professional societies advance the discipline.
- Major cancer centers are increasingly adopting integrative oncology practices.
Conclusions:
- Integrative oncology offers a holistic, evidence-informed approach to cancer care.
- Addressing disparities in access and education is crucial for field maturation.
- Rigorous whole-systems research is needed to further advance integrative oncology.
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