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Related Concept Videos

Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

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Updated: Jun 23, 2026

Bilayer Microfluidic Device for Combinatorial Plug Production
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Bilayer Microfluidic Device for Combinatorial Plug Production

Published on: December 1, 2023

Integrative oncology: evolution, framework, and future directions.

Lorenzo Cohen1, Eran Ben-Arye2,3,4

  • 1Department of Palliative, Rehabilitation, & Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Frontiers in Oncology
|June 22, 2026
PubMed
Summary
This summary is machine-generated.

Integrative oncology combines conventional cancer treatments with mind-body practices, natural products, and lifestyle strategies. This patient-centered approach aims to improve wellbeing and quality of life for cancer patients.

Keywords:
integrative medicinelifestyleoncologyquality of lifesafetysurvivorship

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Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
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Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

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Last Updated: Jun 23, 2026

Bilayer Microfluidic Device for Combinatorial Plug Production
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Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

Area of Science:

  • Integrative oncology research
  • Evidence-based cancer care
  • Patient-centered treatment models

Background:

  • Cancer treatment has evolved beyond tumor-directed modalities.
  • Recognizes the interplay of biological, behavioral, psychosocial, and environmental factors in patient outcomes.
  • Integrative oncology emerged from patient needs and limitations of purely biomedical frameworks.

Purpose of the Study:

  • To outline the historical trajectory and scientific foundations of integrative oncology.
  • To describe clinical models and future opportunities in the field.
  • To highlight the potential of integrative oncology to transform cancer care.

Main Methods:

  • Review of historical development and scientific evidence in integrative oncology.
  • Analysis of clinical models and patient-centered approaches.
  • Discussion of challenges and future research directions.

Main Results:

  • Integrative oncology integrates diverse factors for enhanced patient wellbeing.
  • Evidence-based guidelines and professional societies advance the discipline.
  • Major cancer centers are increasingly adopting integrative oncology practices.

Conclusions:

  • Integrative oncology offers a holistic, evidence-informed approach to cancer care.
  • Addressing disparities in access and education is crucial for field maturation.
  • Rigorous whole-systems research is needed to further advance integrative oncology.