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Updated: Jun 23, 2026

Laser Microdissection-Based Protocol for the LC-MS/MS Analysis of the Proteomic Profile of Neuromelanin Granules
07:35

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Published on: December 16, 2021

Response to: Neuromelanin? T 1 shortening is a necessary condition

Jean-Baptiste Pérot1,2, Marta Gonzalez-Sepulveda3, Miquel Vila3,4

  • 1Paris Brain Institute-ICM, MOVIT team, Sorbonne Université, Inserm U1127, CNRS 7225, Hôpital Pitié-Salpêtriere, Paris 75013, France.

Brain Communications
|June 22, 2026
PubMed
Abstract

No abstract available in PubMed .

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Pigmentation01:19

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...